Oh no. Do you think she is ill? Caitlins routine is messed up after xmas & is sleeping at the wrong times and harder to settle to sleep. Was 10pm the past 2 nights before she was settled.
Phone out of hrs doctor if you think she is sick/in pain. Does she still have that temperature she had last week? If you really worried ring the dr or take her down to A&E. Better safe than sorry, though if you dont think its that serious eg no temp, has taken fluid today, had wet nappies maybe it will just be a case of waiting it out until morning and seeing if she still not herself. Im used to Caitlin screaming and being a monkey at this hr, but granted she would usually have had a few hrs kip before she starts & id be worried to if she hadnt slept at all by now.
Sorry im not much help. Its hard to make a judgement when I cant see her/know what her normal form is. Hope she is all right. x